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KMID : 0363420220360030035
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Journal of Korean Oriental Pediatrics
2022 Volume.36 No. 3 p.35 ~ p.48
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Trend of Clinical Studies on Herbal Medicine Treatment for IgA Nephropathy in Children
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Jeong Ji-Eun
Jeong Min-Jeong
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Abstract
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Objectives : The purpose of this study is to review relevant clinical studies to investigate the effectiveness of herbal medicines for IgA (Immunoglobulin A) nephropathy in children.
Methods : Studies on herbal treatment for IgA nephropathy were searched and analyzed through electronic databases such as PubMed, EMBASE, China National Knowledge Infrastructure, Wanfang, CiNii, J-STAGE, Oriental Medicine
Advanced Searching Integrated System and Science ON. Studies included Randomized controlled trials and case series.
Results : We selected nine studies and analyzed the findings. In most studies, improvement of IgA nephropathy was observed after treatment, and was evaluated using factors as 24 hour urine protein, hematuria, Scr (serum creatinine) and BUN (blood urea nitrogen). The most commonly used herbs for IgA nephropathy were Poria cocos (茯?), Astragalus membranaceus (黃?), and Rehmannia glutinosa (生地黃).
Conclusions : Based on the results of the clinical studies, we identified that herbal medicine is an effective treatment for IgA nephropathy. However, additional systematic clinical studies are necessary to prove its effect and safety.
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KEYWORD
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IgA nephropathy, Berger’s disease, Herbal medicine
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